2. Natural Products
  3. Marine natural products
  4. Marine microorganism

Marine microorganism

Marine microorganism (35):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15141
    Staurosporine 62996-74-1 99.98%
    Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer.
    Staurosporine
  • HY-10985
    Marizomib 437742-34-2 99.55%
    Marizomib (Salinosporamide A) is a second-generation, irreversible, brain-penetrant, pan-proteasome inhibitor. Marizomib inhibits the CT-L (β5), CT-T-laspase-like (C-L, β1) and trypsin-like (T-L, β2) activities of the 20S proteasome (IC50=3.5, 28, and 430 nM, respectively).
    Marizomib
  • HY-N6769
    Radicicol 12772-57-5 99.63%
    Radicicol is an inhibitor of Hsp90 with an IC50 value < 1 μM, and leads to proteasomal degradation. Radicicol exhibits inhibition on PDK with IC50s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC50 value of 16.04 μM.
    Radicicol
  • HY-W001963
    Pyrrole-2-carboxylic acid 634-97-9 99.96%
    Pyrrole-2-carboxylic acid is a natural alkaloid from the marine bacterium Pelomonas puraquae sp. Nov.
    Pyrrole-2-carboxylic acid
  • HY-N9251
    Cyclo(Ile-Ala) 90821-99-1 99.12%
    Cyclo(Ile-Ala) is found in marine actinomycete 11014 I..
    Cyclo(Ile-Ala)
  • HY-N12761
    Penpaxilloids A
    Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A is also an α-glucosidase (α-glucosidase) inhibitor with anti-inflammatory activity.
    Penpaxilloids A
  • HY-N12847
    Biselyngbyolide B 1784755-74-3
    Biselyngbyolide B is an anticancer marine macrolide that can be isolated from the marine cyanobacterium Lyngbya sp.Biselyngbyolide B is an ER stress inducer.
    Biselyngbyolide B
  • HY-N7078
    Spiculisporic acid 469-77-2 ≥98.0%
    Spiculisporic acid is a γ-butenolide isolated from the cultue of Aspergillus sp. Spiculisporic acid is a microbial biosurfactant and has anti-oxidative stress actions.
    Spiculisporic acid
  • HY-113972
    Methyl mycophenolate 31858-66-9 99.27%
    Methyl mycophenolate is a methyl ester of mycophenolic acid and is also found in marine-derived fungus Phaeosphaeria spartinae.
    Methyl mycophenolate
  • HY-125538
    Deoxybrevianamide E 34610-68-9 99.2%
    Deoxybrevianamide E, an indole alkaloid, is a biosynthetic precursor for advanced metabolites isolated from the marine-derived Aspergillus sp..
    Deoxybrevianamide E
  • HY-126708
    Luisol A 225110-59-8 ≥99.0%
    Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, is an anthraquinone antibiotic analog.
    Luisol A
  • HY-N12613
    Sydowimide A
    Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC50 values of 1.5, 2.4 and 18.83 μM, respectively.
    Sydowimide A
  • HY-113604
    Pentabromopseudilin 10245-81-5
    Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour and phytotoxic activities. PBrP is a reversible and allosteric inhibitor of myosin Va (MyoVa). PBrP also is a potent inhibitor of transforming growth factor-β (TGF-β) activity. PBrP can be used for the research of fibrotic diseases and cancer.
    Pentabromopseudilin
  • HY-116479
    Citromycetin 478-60-4
    Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp.
    Citromycetin
  • HY-121133
    (-)-Cyclopenol 20007-85-6
    (-)-Cyclopenol is a fungal metabolite isolated from an Australian marine-derived isolate of Aspergillus versicolor (MST-MF495) .
    (-)-Cyclopenol
  • HY-122404
    Xantocillin 580-74-5
    Xantocillin (Xanthocillin X) is a marine agent extracted from Penicillium commune, induces autophagy through inhibition of the MEK/ERK pathway.
    Xantocillin
  • HY-130995
    Agrochelin 247115-74-8
    Agrochelin, an alkaloid cytotoxic antibiotic, is produced by the fermentation of a marine Agrobacterium sp. Agrochelin has cytotoxic activity in tumor cell lines.
    Agrochelin
  • HY-130996
    Diacetyl Agrochelin 247115-75-9
    Diacetyl Agrochelin is an acetyl derivative of Agrochelin, which is produced by the fermentation of a marine Agrobacterium sp. Diacetyl Agrochelin has cytotoxic activity in tumor cell lines.
    Diacetyl Agrochelin
  • HY-136293
    Mechercharmycin A 822520-96-7
    Mechercharmycin A is a cytotoxic substance isolated from marine-derived Thermoactinomyces sp. YM3-251. Mechercharmycin A exhibits relatively strong antitumor activity.
    Mechercharmycin A
  • HY-137990
    Questin 3774-64-9
    Questin is an antibacterial agent isolated from marine Aspergillus flavipes. Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 µg/mL, 62.5 µg/mL, 62.5 µg/mL, and 125 µg/mL.
    Questin